Ephrin A1 (EFNA1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-150 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 19-205 amino acids of human ephrin-A1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	ephrin A1
Database Link	NP_004419 Entrez Gene 13636 MouseEntrez Gene 94268 RatEntrez Gene 1942 Human UniProt ID P20827
Background	This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events; especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships; ephrins are divided into the ephrin-A (EFNA) class; which are anchored to the membrane by a glycosylphosphatidylinositol linkage; and the ephrin-B (EFNB) class; which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2; EPHA4; EPHA5; EPHA6; and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
Synonyms	B61; ECKLG; EFL1; EPLG1; LERK-1; LERK1; TNFAIP4
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Axon guidance

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