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CD11a (ITGAL) Rabbit Polyclonal Antibody
CAT＃: TA321452S
Anti-ITGAL Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 15-50 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm, Cell membrane |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 1158-1170 amino acids of Human integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | integrin subunit alpha L |
| Database Link | |
| Background | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1); which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands; ICAMs 1-3 (intercellular adhesion molecules 1 through 3); and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.? |
| Synonyms | CD11A; LFA-1; LFA1A |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, Viral myocarditis |
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Rabbit anti-ITGAL Polyclonal Antibody
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