OPCML Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse brain tissue
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 28-322 amino acids of human opioid binding protein/cell adhesion molecule-like
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	38 kDa
Gene Name	opioid binding protein/cell adhesion molecule-like
Database Link	NP_001012393 Entrez Gene 116597 RatEntrez Gene 330908 MouseEntrez Gene 4978 Human UniProt ID Q14982
Background	This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids; exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution; it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	IGLON1; OBCAM; OPCM
Reference Data
Protein Families	Druggable Genome, Transmembrane

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