EP4 (PTGER4) Rabbit Polyclonal Antibody
CAT#: TA321244S
Anti-PTGER4 Rabbit Polyclonal Antibody
Size: 100 ul
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CN¥ 800.00
CN¥ 1,280.00
货期*
2周
规格
经常一起买 (2)
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 500-2000 WB positive control: LoVo cells |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 458-473 amino acids of Human prostaglandin E receptor 4 (subtype EP4) |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 53 kDa |
Gene Name | prostaglandin E receptor 4 |
Database Link | |
Background | The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1); regulate the level and stability of cyclooxygenase-2 mRNA; and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system; osteoporosis; as well as initiation of skin immune responses. |
Synonyms | EP4; EP4R |
Reference Data | |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
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