Cytokeratin 18 (KRT18) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: K562 cell IHC: 25-100 Positive control: Human cervical cancer Predicted cell location: Cytoplasm and cell membrane
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 130-430 amino acids of human keratin 18
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	keratin 18
Database Link	NP_000215 Entrez Gene 16668 MouseEntrez Gene 294853 RatEntrez Gene 3875 Human UniProt ID P05783
Background	KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Synonyms	CYK18; K18
Reference Data
Protein Pathways	Pathogenic Escherichia coli infection

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