ATG4C Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 2-6µg/ml
Reactivity	Human, Dog, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	C- terminus of NP_116241.2; NP_835739.1 (EDEKKQLKRFSTEE)
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	autophagy related 4C cysteine peptidase
Database Link	NP_116241 Entrez Gene 489561 DogEntrez Gene 84938 Human UniProt ID Q96DT6
Background	Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms	APG4-C; APG4C; AUTL1; AUTL3
Note	Reported variants represent identical protein: NP_116241.2, NP_835739.1
Reference Data
Protein Families	Protease
Protein Pathways	Regulation of autophagy

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