CD45 (PTPRC) Rat Monoclonal Antibody [Clone ID: RA3-6B2]

Specifications

Product Data
Clone Name	RA3-6B2
Applications	FC
Recommend Dilution	Flow, IHC, IP
Reactivity	Human, Mouse
Host	Rat
Clonality	Monoclonal
Formulation	Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	protein tyrosine phosphatase, receptor type C
Database Link	NP_563579 Entrez Gene 19264 MouseEntrez Gene 5788 Human UniProt ID P08575
Background	The RA3-6B2 monoclonal antibody reacts with exon A-restricted isoform of mouse CD45, a 220 kDa surface molecule. CD45R/B220 epitope is mainly expressed by the B cell lineage from early Pro-B to mature B cells. However, some activated T cells, lymphokine activated killer cells (LAK), NK cell progenitors in the bone marrow, and T cells of the lpr/lpr mutant mouse also express this antigen.
Synonyms	B220; CD45; CD45R; GP180; LCA; LY5; T200
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Phosphatase, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Fc gamma R-mediated phagocytosis, Primary immunodeficiency, T cell receptor signaling pathway

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