FREM2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ICC: 20 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	FREM2 antibody was raised against a 19 amino acid synthetic peptide near the center of human FREM2.
Formulation	FREM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	FREM2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	FRAS1 related extracellular matrix protein 2
Database Link	NP_997244 Entrez Gene 242022 MouseEntrez Gene 341640 Human UniProt ID Q5SZK8
Background	FREM2 Antibody: FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
Synonyms	DKFZp686J0811; DKFZp781I048; KIAA1074
Reference Data
Protein Families	Transmembrane

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