TMPRSS11A Chicken Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Chicken
Clonality	Polyclonal
Immunogen	ECRG1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG1.
Formulation	ECRG1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	ECRG1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	transmembrane protease, serine 11A
Database Link	NP_872412 Entrez Gene 194597 MouseEntrez Gene 686581 RatEntrez Gene 339967 Human UniProt ID Q6ZMR5
Background	ECRG1 Antibody: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.
Synonyms	ECRG1
Reference Data
Protein Families	Druggable Genome, Transmembrane

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