CAVIN3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP.
Formulation	PRKCDBP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	PRKCDBP Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29 kDa
Gene Name	protein kinase C delta binding protein
Database Link	NP_659477 Entrez Gene 109042 MouseEntrez Gene 112464 Human UniProt ID Q969G5
Background	PRKCDBP Antibody: The protein kinase C delta (PKC-δ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.
Synonyms	cavin-3; CAVIN3; HSRBC; SRBC
Reference Data
Protein Families	Druggable Genome

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