YPEL3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	YPEL3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human YPEL3.
Formulation	YPEL3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	YPEL3 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	yippee like 3
Database Link	NP_113665 Entrez Gene 66090 MouseEntrez Gene 293491 RatEntrez Gene 83719 Human UniProt ID P61236
Background	YPEL3 Antibody: YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
Synonyms	MGC10500
Reference Data

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