NLRX1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	NOD5 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NOD5.
Formulation	NOD5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	NOD5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NLR family member X1
Database Link	NP_078894 Entrez Gene 270151 MouseEntrez Gene 315599 RatEntrez Gene 79671 Human UniProt ID Q86UT6
Background	NOD5 Antibody: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-κB and JNK pathways by inducing reactive oxygen species production.
Synonyms	CLR11.3; DLNB26; NOD5; NOD9; NOD26
Reference Data
Protein Pathways	RIG-I-like receptor signaling pathway

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