UHRF1BP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	UHRF1BP1 antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1.
Formulation	UHRF1BP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	UHRF1BP1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	UHRF1 binding protein 1
Database Link	NP_060224 Entrez Gene 224648 MouseEntrez Gene 54887 Human UniProt ID Q6BDS2
Background	UHRF1BP1 Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.
Synonyms	C6orf107; dJ349A12.1; ICBP90
Reference Data

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