PRICKLE4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 0.25 ug/mL, ICC: 5 ug/mL, IF: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	PRICKLE4 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PRICKLE4.
Formulation	PRICKLE4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	PRICKLE4 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	prickle planar cell polarity protein 4
Database Link	NP_037529 Entrez Gene 29964 Human UniProt ID Q2TBC4
Background	PRICKLE4 Antibody: PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins. It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus. Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation. Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role.
Synonyms	C6orf49; OBTP; OEBT; TOMM6
Reference Data

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