CCDC106 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CCDC106 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CCDC106.
Formulation	CCDC106 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	CCDC106 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	coiled-coil domain containing 106
Database Link	NP_037433 Entrez Gene 232821 MouseEntrez Gene 499071 RatEntrez Gene 29903 Human UniProt ID Q9BWC9
Background	CCDC106 Antibody: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
Synonyms	HSU79303; ZNF581
Reference Data

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