BATF Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 0.5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	BATF antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BATF.
Formulation	BATF Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	BATF Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	14 kDa
Gene Name	basic leucine zipper ATF-like transcription factor
Database Link	NP_006390 Entrez Gene 53314 MouseEntrez Gene 299206 RatEntrez Gene 10538 Human UniProt ID Q16520
Background	BATF Antibody: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
Synonyms	B-ATF; BATF1; SFA-2; SFA2
Reference Data
Protein Families	Transcription Factors

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