RUSC2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	RUSC2 antibody was raised against an 18 amino acid synthetic peptide from near the amino terminus of human RUSC2.
Formulation	RUSC2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	RUSC2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	RUN and SH3 domain containing 2
Database Link	NP_055621 Entrez Gene 100213 MouseEntrez Gene 9853 Human UniProt ID Q8N2Y8
Background	RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
Synonyms	Iporin
Reference Data

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