RUSC2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	ICC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	RUSC2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RUSC2.
Formulation	RUSC2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	RUSC2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	RUN and SH3 domain containing 2
Database Link	NP_001098673 Entrez Gene 9853 Human UniProt ID Q8N2Y8
Background	RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
Synonyms	Iporin
Reference Data

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