ULK2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	ULK2 antibody was raised against a 17 amino acid peptide near the center of human ULK2 .
Formulation	ULK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	ULK2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 105, 114 kDa; Observed: 100 kDa
Gene Name	unc-51 like autophagy activating kinase 2
Database Link	NP_055498 Entrez Gene 9706 Human UniProt ID Q8IYT8
Background	ULK2 Antibody: ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
Synonyms	ATG1B; Unc51.2
Reference Data

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