TSPY1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Rabbit polyclonal TSPY1S antibody was raised against a 13 amino acid peptide near the carboxy terminus of human TSPY1S.
Formulation	TSPY1S Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TSPY1S Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	32 kDa
Gene Name	testis specific protein, Y-linked 1
Database Link	NP_001184171 Entrez Gene 7258 Human UniProt ID Q01534
Background	TSPY1S Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
Synonyms	CT78; DYS14; pJA923; TSPY
Reference Data

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