Translin (TSN) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin.
Formulation	Translin Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Translin Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	translin
Database Link	NP_004613 Entrez Gene 22099 MouseEntrez Gene 60381 RatEntrez Gene 7247 Human UniProt ID Q15631
Background	Translin Antibody: Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
Synonyms	BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN
Reference Data

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