TLR4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	TLR4 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TLR4.
Formulation	TLR4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TLR4 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	toll like receptor 4
Database Link	NP_612564 Entrez Gene 7099 Human UniProt ID O00206
Background	TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.
Synonyms	ARMD10; CD284; TLR-4; TOLL
Reference Data

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