PLAGL2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	PLAGL2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PLAGL2.
Formulation	PLAGL2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	PLAGL2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	55 kDa
Gene Name	PLAG1 like zinc finger 2
Database Link	NP_002648 Entrez Gene 54711 MouseEntrez Gene 296281 RatEntrez Gene 5326 Human UniProt ID Q9UPG8
Background	PLAGL2 Antibody: The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.
Synonyms	ZNF900
Reference Data
Protein Families	Transcription Factors

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