Leucyl cystinyl aminopeptidase (LNPEP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, IF: 20 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	LNPEP antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human LNPEP.
Formulation	LNPEP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	LNPEP Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	113 kDa
Gene Name	leucyl/cystinyl aminopeptidase
Database Link	NP_005566 Entrez Gene 4012 Human UniProt ID Q9UIQ6
Background	LNPEP Antibody: LNPEP, also known as insulin-responsive aminopeptidase (IRAP), was initially identified as an abundant protein that is associated with specialized endosomes termed GLUT4 storage vesicles (GSVs) in adipocytes. The luminal domain of LNPEP contains an aminopeptidase activity that is involved in peptide hormone processing and antigenic peptide processing. LNPEP is also a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to the GSVs.
Synonyms	CAP; IRAP; P-LAP; PLAP
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein, Transmembrane
Protein Pathways	Renin-angiotensin system

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