KPNA3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	KPNA3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy end of human KPNA3.
Formulation	KPNA3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	KPNA3 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	karyopherin subunit alpha 3
Database Link	NP_002258 Entrez Gene 16648 MouseEntrez Gene 361055 RatEntrez Gene 3839 Human UniProt ID O00505
Background	KPNA3 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is silimar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia.
Synonyms	hSRP1; IPOA4; SRP1; SRP1gamma; SRP4
Reference Data

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