TLX2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	TLX2 antibody was raised against an 18 amino acid peptide near the amino terminus of human TLX2.
Formulation	TLX2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TLX2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 31 kDa; Observed: 30 kDa
Gene Name	T-cell leukemia homeobox 2
Database Link	NP_057254 Entrez Gene 21909 MouseEntrez Gene 680117 RatEntrez Gene 3196 Human UniProt ID O43763
Background	TLX2 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.
Synonyms	HOX11L1; NCX
Reference Data
Protein Families	Transcription Factors

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