DAP1 (DAP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	DAP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DAP.
Formulation	DAP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	DAP Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 11 kDa; Observed: 11 kDa
Gene Name	death-associated protein
Database Link	NP_004385 Entrez Gene 64322 RatEntrez Gene 223453 MouseEntrez Gene 1611 Human UniProt ID P51397
Background	DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2).
Synonyms	MGC99796
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.