CD48 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	SLAMF2 antibody was raised against a 19 amino acid synthetic peptide near the center of human SLAMF2.
Formulation	SLAMF2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	SLAMF2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CD48 molecule
Database Link	NP_001769 Entrez Gene 12506 MouseEntrez Gene 245962 RatEntrez Gene 962 Human UniProt ID P09326
Background	SLAMF2 Antibody: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.
Synonyms	BCM1; BLAST; BLAST1; hCD48; mCD48; MEM-102; SLAMF2
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Natural killer cell mediated cytotoxicity

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