BOK Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK.
Formulation	BOK Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	BOK Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	BCL2-related ovarian killer
Database Link	NP_115904 Entrez Gene 666 Human UniProt ID Q9UMX3
Background	BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.
Synonyms	BCL2L9; BOKL
Reference Data
Protein Families	Druggable Genome

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