AHSP Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1:2,000 - 1:10,000, WB: 1:500-1:1000, IHC: 1:8000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Anti-AHSP Antibody was produced from whole rabbit serum prepared by repeated immunizations with the full length human AHSP protein.
Formulation	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	alpha hemoglobin stabilizing protein
Database Link	NP_057717 Entrez Gene 170812 MouseEntrez Gene 51327 Human UniProt ID Q9NZD4
Synonyms	EDRF; ERAF
Note	AHSP Antibody detects Alpha hemoglobin stabilizing protein (AHSP). AHSP acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. AHSP binds free a-globin to promote its folding and inhibit its ability to produce damaging reactive oxygen species. Reduced AHSP levels correlate with increased severity of b-thalassemia in some human cohorts.
Reference Data

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