MAD2 (MAD2L1) Rabbit Polyclonal Antibody

CAT#: TA319158

Rabbit polyclonal anti-MAD2L1 antibody



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CNY 8,025.00


货期*
5周

规格
    • 100 ug

Product images

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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1:2,000 - 1:10,000, WB: 1:500 - 1:2,000, IF: User Optimized
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues 3-13 of Human MAD2L1 protein.
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name MAD2 mitotic arrest deficient-like 1 (yeast)
Synonyms HSMAD2; MAD2
Note MAD2L1 (also called mitotic spindle assembly checkpoint protein, MAD2A, MAD2-like 1 and HsMAD2) is a component of the mitotic spindle assembly checkpoint monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. MAD2L1 inhibits the activity of the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. This protein has a nuclear localization.
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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