SIM1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1-3ug/ml
Reactivity	Human, Mouse, Rat, Dog, Cow, Pig
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-SGDRYRTEQYQS, from the internal region of the protein sequence according to NP_005059.2.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	single-minded family bHLH transcription factor 1
Database Link	NP_005059 Entrez Gene 20464 MouseEntrez Gene 309888 RatEntrez Gene 481937 DogEntrez Gene 6492 Human UniProt ID P81133
Background	SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome. [provided by RefSeq]
Synonyms	bHLHe14
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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