Slc18a2 Sheep Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Rat
Host	Sheep
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to amino acid residues from the intracellular C-terminal region conjugated to KLH
Formulation	100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	57 kDa
Gene Name	solute carrier family 18 (vesicular monoamine), member 2
Database Link	NP_766111 Entrez Gene 25549 Rat UniProt ID Q8BRU6
Background	The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002). [supplied by OMIM]
Synonyms	MGC26538; MGC120477; MGC120478; SVAT; SVMT; VAT2; VMAT2
Reference Data

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