Retinoic Acid Receptor beta (RARB) Mouse Monoclonal Antibody [Clone ID: 336]

Specifications

Product Data
Clone Name	336
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Formulation	100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	48 kDa
Gene Name	retinoic acid receptor beta
Database Link	NP_057236 Entrez Gene 5915 Human UniProt ID P10826
Background	This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. [provided by RefSeq]
Synonyms	HAP; MCOPS12; NR1B2; RARbeta1; RRB2
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways	Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer

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