Progesterone Receptor (PGR) Mouse Monoclonal Antibody [Clone ID: 1154]

Specifications

Product Data
Clone Name	1154
Applications	WB
Recommend Dilution	WB: 1:1000, IHC: 1:1000
Reactivity	Human
Modifications	Phospho-specific
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser190 conjugated to KLH
Formulation	100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	90/120 kDa
Gene Name	progesterone receptor
Database Link	NP_000917 Entrez Gene 5241 Human UniProt ID P06401
Background	This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq]
Synonyms	NR3C3; PR
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways	Oocyte meiosis, Progesterone-mediated oocyte maturation

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