RSK1 p90 (RPS6KA1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse, Chicken, Rat, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 303 and 527 of RSK1
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	84 kDa
Gene Name	ribosomal protein S6 kinase A1
Database Link	NP_001006666 Entrez Gene 20111 MouseEntrez Gene 81771 RatEntrez Gene 6195 Human UniProt ID Q15418
Background	This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Synonyms	HU-1; MAPKAPK1A; p90Rsk; RSK; RSK1
Note	Seq homology of immunogen across species: Mouse (97%), Chicken (91%), Rat (95%), Bovine (98%)
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Long-term potentiation, MAPK signaling pathway, mTOR signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation

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