Haptoglobin (HP) Rabbit Polyclonal Antibody

CAT#: TA308899

Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)



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CNY 6,281.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution ELISA:; WB:1:500-1:3000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 129 and 375 of (Uniprot ID#P00738)
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 38 kDa
Gene Name haptoglobin
Background This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms BP; HP2ALPHA2; HPA1S
Reference Data
Protein Families Druggable Genome, Protease, Secreted Protein, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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