Mannose Phosphate Isomerase (MPI) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 150 and 423 of MPI (Uniprot ID#P34949)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	47 kDa
Gene Name	mannose phosphate isomerase
Database Link	NP_002426 Entrez Gene 110119 MouseEntrez Gene 300741 RatEntrez Gene 4351 Human UniProt ID P34949
Background	Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. [provided by RefSeq]
Synonyms	CDG1B; PMI; PMI1
Note	Seq homology of immunogen across species: Mouse (84%), Rat (86%), Bovine (92%)
Reference Data
Protein Families	ES Cell Differentiation/IPS
Protein Pathways	Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

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