DCAF12 Chicken Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Chicken
Clonality	Polyclonal
Immunogen	TCC52 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human TCC52.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Affinity chromatography purified via peptide column
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	DDB1 and CUL4 associated factor 12
Database Link	NP_056212 Entrez Gene 68970 MouseEntrez Gene 313296 RatEntrez Gene 682812 RatEntrez Gene 25853 Human UniProt ID Q5T6F0
Background	Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
Synonyms	CT102; KIAA1892; TCC52; WDR40A
Reference Data

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