GNPDA2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, ICC:4 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	GNPDA2 antibody was raised against an 8 amino acid peptide near the carboxy terminus of human GNPDA2.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Affinity chromatography purified via peptide column
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	glucosamine-6-phosphate deaminase 2
Database Link	NP_612208 Entrez Gene 67980 MouseEntrez Gene 132789 Human UniProt ID Q8TDQ7
Background	Glucosamine-6-phosphate deaminase (GNPDA) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered, and is closer in structure and activity to the E. coli enzyme than GNPDA1. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2. GNPDA2 antibody is predicted to not cross-react with GNPDA1.
Synonyms	GNP2; SB52
Reference Data
Protein Pathways	Amino sugar and nucleotide sugar metabolism, Metabolic pathways

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