Klra3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 2 ug/mL
Reactivity	Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLRA3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA3.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Affinity chromatography purified via peptide column
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	killer cell lectin-like receptor, subfamily A, member 3
Database Link	AAI32525 Entrez Gene 16634 Mouse UniProt ID Q64329
Background	KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide –receptive H-2Kb. This antibody may cross-react with other LY49 receptors.
Synonyms	5E6; Ly49c; Nk-2; NK-2.1; Nk2; Nk2.1
Reference Data

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