BLBP (FABP7) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 0.5 - 2 ug/mL, ICC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	FABP7 antibody was raised against a 17 amino acid peptide from near the center of human FABP7.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Affinity chromatography purified via peptide column
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	fatty acid binding protein 7
Database Link	NP_001437 Entrez Gene 2173 Human UniProt ID O15540
Background	FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.
Synonyms	B-FABP; BLBP; FABPB; LTR2-FABP7; MRG
Reference Data
Protein Pathways	PPAR signaling pathway

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