Interferon beta (IFNB1) Rabbit Polyclonal Antibody
CNY 5,808.00
货期*
5周
规格
Cited in 2 publications. |
经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | WB: 5 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | IFN-beta antibody was raised against a 17 amino acid synthetic peptide from near the center of human IFN-b. The immunogen is located within amino acids 110 - 160 of IFN-beta. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Affinity chromatography purified via peptide column |
Conjugation | Unconjugated |
Storage Condition | Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures. |
Gene Name | interferon beta 1 |
Database Link | |
Background | Type I Interferons (IFN-a/b) are produced primarily in response to viral infection by “Natural IFN-producing cells" (IPCs) as part of the host immune response and can also inhibit the development of tumors. IFN-b binding by its receptor results in the activation of the tyrosine kinases Jak1 and Tyk2 and phosphorylation of members of the STAT family of transcription factors, leading to the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-b. IFN-b is currently used clinically for treatment of tumors, infections and multiple sclerosis. |
Synonyms | IFB; IFF; IFNB |
Reference Data |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
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Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling
,Jie, C;Luo, Z;Chen, H;Wang, M;Yan, C;Mao, ZF;Xiao, GK;Kurihara, H;Li, YF;He, RR;,
Oncotarget
,PubMed ID 29285277
[IFNB1]
|
New insights into the effects and mechanism of a classic traditional Chinese medicinal formula on influenza prevention
,Chen, H;Jie, C;Tang, L;Meng, H;Li, X;Li, Y;Chen, L;Yan, C;Kurihara, H;Li, Y;He, R;,
Phytomedicine
,PubMed ID 28314479
[IFNB1]
|
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