Caspase-7 (CASP7) Rabbit Polyclonal Antibody

CAT#: TA306201

Rabbit Polyclonal Caspase-7 Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

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经常一起买 (4)
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    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 0.5 - 1 ug/mL, ICC: 2 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Caspase-7 antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human Caspase-7.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name caspase 7
Background Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3 (4). Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms (4). Caspase-7 activity can be directly inhibited by XIAP expression (5).
Synonyms CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Alzheimer's disease, Apoptosis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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