TICAM2 Rabbit Polyclonal Antibody

CAT#: TA306163

Rabbit Polyclonal TIRP Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

Cited in 2 publications.

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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution WB: 1 ug/mL, ICC: 2 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen TIRP antibody was raised against a peptide corresponding to amino acids near the C-terminus of human TIRP.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Ion exchange chromatography purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name toll like receptor adaptor molecule 2
Background TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB (5). Expression of TIRP appears to be essential for TLR4 signalling (6).
Synonyms MyD88-4; TICAM-2; TIRAP3; TIRP; TRAM
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)

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