MAD2 (MAD2L1) Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 0.5-2ug/ml.
Reactivity	Human, Mouse, Rat, Dog, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-KVNSMVAYKIPVND, from the C Terminus of the protein sequence according to NP_002349.1.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	MAD2 mitotic arrest deficient-like 1 (yeast)
Database Link	NP_002349 Entrez Gene 56150 MouseEntrez Gene 297176 RatEntrez Gene 476070 DogEntrez Gene 4085 Human UniProt ID Q13257
Background	MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq]
Synonyms	HSMAD2; MAD2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

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