Arginase 1 (ARG1) Goat Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, PEP-ELISA, WB
Recommend Dilution	ELISA: 1:2,000. WB: 0.03-0.1µg/ml.
Reactivity	Human, Mouse, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-REGNHKPIDYLNPPK, from the C Terminus of the protein sequence according to NP_000036.2.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	arginase 1
Database Link	NP_000036 Entrez Gene 11846 MouseEntrez Gene 474823 DogEntrez Gene 383 Human UniProt ID P05089
Background	Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]
Synonyms	arginase; arginase 1; liver; liver-type arginase; OTTHUMP00000017209; type I arginase
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arginine and proline metabolism, Metabolic pathways

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