STAM2 Goat Polyclonal Antibody

Specifications

Product Data
Applications	FC, PEP-ELISA, WB
Recommend Dilution	ELISA: 1:8,000. WB: 1-3µg/ml.
Reactivity	Human, Mouse, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-QSIDPTDSKPDSQD, from the internal region of the protein sequence according to NP_005834.3.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	signal transducing adaptor molecule 2
Database Link	NP_005834 Entrez Gene 56324 MouseEntrez Gene 476150 DogEntrez Gene 10254 Human UniProt ID O75886
Background	The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq]
Synonyms	Hbp; STAM2A; STAM2B
Reference Data
Protein Pathways	Endocytosis, Jak-STAT signaling pathway

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