MCL1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:2,000. WB: 1-3µg/ml.
Reactivity	Human, Mouse, Rat, Dog, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-AGVGAGLAYLIR, from the C Terminus of the protein sequence according to NP_068779.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	myeloid cell leukemia 1
Database Link	NP_068779 Entrez Gene 17210 MouseEntrez Gene 60430 RatEntrez Gene 403537 DogEntrez Gene 4170 Human UniProt ID Q07820
Background	The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. [provided by RefSeq]
Synonyms	bcl2-L-3; BCL2L3; EAT; Mcl-1; mcl1; MCL1-ES; MCL1L; MCL1S; TM
Reference Data
Protein Families	Druggable Genome, Transmembrane

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