DOCK1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 3-4µg/ml.
Reactivity	Human, Mouse, Rat, Dog, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-TTRKQTSVDSGIVQ, from the C Terminus of the protein sequence according to NP_001371.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	dedicator of cytokinesis 1
Database Link	NP_001371 Entrez Gene 309081 RatEntrez Gene 330662 MouseEntrez Gene 486934 DogEntrez Gene 1793 Human UniProt ID Q14185
Background	This gene product binds to the SH3 domain of CRK protein. It may regulate cell surface extension and may have a role in the cell surface extension of an engulfing cell around a dying cell during apoptosis. [provided by RefSeq]
Synonyms	ced5; DOCK180
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Focal adhesion, Regulation of actin cytoskeleton

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